Definition
A "gene mutation" is a change in the DNA sequence that makes up a gene. This change can alter the protein that the gene codes for, or prevent the gene from functioning properly. Think of it as a typo in the instruction manual for building a specific protein in your body. Mutations can range from small changes affecting a single DNA base to larger alterations affecting entire genes. These mutations can be inherited or arise spontaneously. The consequences can vary from no effect to serious diseases. A gene mutation fundamentally alters the instructions for a particular protein.