Definition
A hepadnavirus is a family of viruses that infect the liver cells of various animals, including humans. They are known for causing hepatitis, an inflammation of the liver. Think of them as liver-specific invaders. These viruses have a unique replication strategy involving reverse transcription of their DNA genome. They can cause chronic infections, leading to liver damage, cirrhosis, and liver cancer. Understanding hepadnaviruses is crucial for preventing and treating liver diseases.