Definition
Poxviruses are a family of large, complex DNA viruses. They are unique because they replicate in the cytoplasm (rather than the nucleus) of the host cell. 🦠 Poxviruses are known for causing skin lesions, such as those seen in smallpox, monkeypox, and cowpox. Some poxviruses can infect humans, while others infect animals. Think of them as the 'skin lesion' viruses. Smallpox, caused by variola virus, was eradicated through vaccination, demonstrating the power of science. Poxviruses remain important for both historical and contemporary reasons.